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Peptidomimetics prepared by tail-to-side chain one component peptide stapling inhibit Alzheimer's amyloid-β fibrillogenesis

Alzheimer's disease (AD) is the most common form of dementia affecting the elderly population worldwide. Despite enormous efforts and considerable advancement in research, no therapeutic agents have come to light to date. However, many peptide-based and small molecule inhibitors interact effici...

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Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Kalita, Sujan, Kalita, Sourav, Paul, Ashim, Sarkar, Amar, Mandal, Bhubaneswar
Format: Artigo
Langue:Inglês
Publié: The Royal Society of Chemistry 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152599/
https://ncbi.nlm.nih.gov/pubmed/34122880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc06076f
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