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Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.

A central event in Alzheimer's disease is the conformational change from normally circulating soluble amyloid beta peptides (A beta) and tau proteins into amyloid fibrils, in the form of senile plaques and neurofibrillary tangles respectively. The apolipoprotein E (apoE) gene locus has recently...

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Détails bibliographiques
Auteurs principaux: Castano, E M, Prelli, F, Wisniewski, T, Golabek, A, Kumar, R A, Soto, C, Frangione, B
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136559/
https://ncbi.nlm.nih.gov/pubmed/7534068
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