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Peptidomimetics prepared by tail-to-side chain one component peptide stapling inhibit Alzheimer's amyloid-β fibrillogenesis

Alzheimer's disease (AD) is the most common form of dementia affecting the elderly population worldwide. Despite enormous efforts and considerable advancement in research, no therapeutic agents have come to light to date. However, many peptide-based and small molecule inhibitors interact effici...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Kalita, Sujan, Kalita, Sourav, Paul, Ashim, Sarkar, Amar, Mandal, Bhubaneswar
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152599/
https://ncbi.nlm.nih.gov/pubmed/34122880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc06076f
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