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The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model

Buruli ulcer (BU) is an emerging infectious disease that causes disfiguring skin ulcers. The causative agent, Mycobacterium ulcerans, secretes toxin called mycolactone that triggers inflammation and immunopathology. Existing treatments are lengthy and consist of drugs developed for tuberculosis. Her...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nat Commun
Κύριοι συγγραφείς: Liu, Yang, Gao, Yamin, Liu, Jianxiong, Tan, Yaoju, Liu, Zhiyong, Chhotaray, Chiranjibi, Jiang, Huofeng, Lu, Zhili, Chiwala, Gift, Wang, Shuai, Makafe, Gaelle, Islam, Md Mahmudul, Hameed, H. M. Adnan, Cai, Xingshan, Wang, Changwei, Li, Xinjie, Tan, Shouyong, Zhang, Tianyu
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355801/
https://ncbi.nlm.nih.gov/pubmed/30705268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08464-y
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