Phenotypic and genotypic characterization of levofloxacin- and moxifloxacin-resistant Mycobacterium tuberculosis clinical isolates in southern China

BACKGROUND: Levofloxacin (LVX) and Moxifloxacin (MXF) are the cornerstones for treatment of multidrug-resistant tuberculosis (MDR-TB). China is one of the highest MDR- and fluoroquinolones (FQ)-resistant TB burdens countries. DNA gyrase encoded by gyr genes is the main target of FQ in Mycobacterium...

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Vydáno v:J Thorac Dis
Hlavní autoři: Hameed, H. M. Adnan, Tan, Yaoju, Islam, Md Mahmudul, Guo, Lingmin, Chhotaray, Chiranjibi, Wang, Shuai, Liu, Zhiyong, Gao, Yamin, Tan, Shouyong, Yew, Wing Wai, Zhong, Nanshan, Liu, Jianxiong, Zhang, Tianyu
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940237/
https://ncbi.nlm.nih.gov/pubmed/31903250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2019.11.03
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