Detection of Novel Gene Mutations Associated with Pyrazinamide Resistance in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China

OBJECTIVE: Pyrazinamide (PZA) is a cornerstone of modern tuberculosis regimens. This study aimed to investigate the performance of genotypic testing of pncA(+) upstream region, rpsA, panD, Rv2783c, and clpC1 genes to add insights for more accurate molecular diagnosis of PZA-resistant (R) Mycobacteri...

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Dettagli Bibliografici
Pubblicato in:Infect Drug Resist
Autori principali: Hameed, HM Adnan, Tan, Yaoju, Islam, Md Mahmudul, Lu, Zhili, Chhotaray, Chiranjibi, Wang, Shuai, Liu, Zhiyong, Fang, Cuiting, Tan, Shouyong, Yew, Wing Wai, Zhong, Nanshan, Liu, Jianxiong, Zhang, Tianyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986415/
https://ncbi.nlm.nih.gov/pubmed/32158237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S230774
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