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Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D β-Lactamases

Class D carbapenemases are enzymes of the utmost clinical importance due to their ability to confer resistance to the last-resort carbapenem antibiotics. We investigated the role of the conserved hydrophobic bridge in the carbapenemase activity of OXA-23, the major carbapenemase of the important pat...

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Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Stewart, Nichole K., Smith, Clyde A., Antunes, Nuno T., Toth, Marta, Vakulenko, Sergei B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355612/
https://ncbi.nlm.nih.gov/pubmed/30530607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02191-18
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