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Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D β-Lactamases
Class D carbapenemases are enzymes of the utmost clinical importance due to their ability to confer resistance to the last-resort carbapenem antibiotics. We investigated the role of the conserved hydrophobic bridge in the carbapenemase activity of OXA-23, the major carbapenemase of the important pat...
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| Udgivet i: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355612/ https://ncbi.nlm.nih.gov/pubmed/30530607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02191-18 |
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