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Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 β-Lactamase

Carbapenem-hydrolyzing class D carbapenemases (CHDLs) are enzymes that produce resistance to the last-resort carbapenem antibiotics, severely compromising the available therapeutic options for the treatment of life-threatening infections. A broad variety of CHDLs, including OXA-23, OXA-24/40, and OX...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Smith, Clyde A., Stewart, Nichole K., Toth, Marta, Vakulenko, Sergei B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761500/
https://ncbi.nlm.nih.gov/pubmed/31358584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01202-19
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