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Ex vivo synthetic immune tissues with T cell signals for differentiating antigen-specific, high affinity germinal center B cells
Most antigen discovery and vaccine development aimed at driving functional B cell responses rely on mouse immunizations studies. To date, there is no 3D ex vivo immune tissues, which are capable of driving antigen-specific B cell responses to rapidly determine the humoral immunogenicity of antigens,...
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| Publicado no: | Biomaterials |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355359/ https://ncbi.nlm.nih.gov/pubmed/30041943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.06.034 |
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