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Organoid Polymer Functionality and Mode of Klebsiella Pneumoniae Membrane Antigen Presentation Regulates Ex Vivo Germinal Center Epigenetics in Young and Aged B Cells

Antibiotic-resistant bacteria are a major global health threat that continues to rise due to a lack of effective vaccines. Of concern are Klebsiella pneumoniae that fail to induce in vivo germinal center B cell responses, which facilitate antibody production to fight infection. Immunotherapies using...

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Detalhes bibliográficos
Publicado no:Adv Funct Mater
Main Authors: Graney, Pamela L., Lai, Kristine, Post, Sarah, Brito, Ilana, Cyster, Jason, Singh, Ankur
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939142/
https://ncbi.nlm.nih.gov/pubmed/33692664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.202001232
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