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Deficiency of IL12p40 (Interleukin 12 p40) Promotes Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysm

OBJECTIVE: Abdominal aortic aneurysm is caused by the accumulation of inflammatory cells in the aortic wall. Our recent studies demonstrated that inhibition of Notch signaling attenuates abdominal aortic aneurysm formation by shifting the macrophage balance towards anti-inflammatory (M2) phenotype....

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Sharma, Neekun, Dev, Rishabh, Belenchia, Anthony M., Aroor, Annayya R., Whaley-Connell, Adam, Pulakat, Lakshmi, Hans, Chetan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355331/
https://ncbi.nlm.nih.gov/pubmed/30580570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311969
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