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AT2R agonist NP‐6A4 mitigates aortic stiffness and proteolytic activity in mouse model of aneurysm

Clinical and experimental studies show that angiotensin II (AngII) promotes vascular pathology via activation of AngII type 1 receptors (AT1Rs). We recently reported that NP‐6A4, a selective peptide agonist for AngII type 2 receptor (AT2R), exerts protective effects on human vascular cells subjected...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Sharma, Neekun, Belenchia, Anthony M., Toedebusch, Ryan, Pulakat, Lakshmi, Hans, Chetan P.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339180/
https://ncbi.nlm.nih.gov/pubmed/32420690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15342
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