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Activation of MEK 1/2 and p42/44 MAPK by Angiotensin II in Hepatocyte Nucleus and their Potentiation by Ethanol

Hepato-subcellular effect of Ang II and ethanol on the p42/44 MAP Kinase and MEK1/2 were investigated in the nucleus of rat hepatocytes. Hepatocytes were treated with ethanol (100 mM) for 24 hr and stimulated with angiotensin II (Ang II, 100 nM, 5 min). The levels of p42/44 MAPK and MEK1/2 were moni...

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Detalhes bibliográficos
Main Authors: Aroor, Annayya R., Lee, Youn Ju, Shukla, Shivendra D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743527/
https://ncbi.nlm.nih.gov/pubmed/19560630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2009.04.001
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