An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

Energy stress, such as ischemia, induces mitochondrial damage and death in the heart. Degradation of damaged mitochondria by mitophagy is essential for the maintenance of healthy mitochondria and survival. Here, we show that mitophagy during myocardial ischemia was mediated predominantly through aut...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Saito, Toshiro, Nah, Jihoon, Oka, Shin-ichi, Mukai, Risa, Monden, Yoshiya, Maejima, Yasuhiro, Ikeda, Yoshiyuki, Sciarretta, Sebastiano, Liu, Tong, Li, Hong, Baljinnyam, Erdene, Fraidenraich, Diego, Fritzky, Luke, Zhai, Peiyong, Ichinose, Shizuko, Isobe, Mitsuaki, Hsu, Chiao-Po, Kundu, Mondira, Sadoshima, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355232/
https://ncbi.nlm.nih.gov/pubmed/30511961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122035
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