An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

Energy stress, such as ischemia, induces mitochondrial damage and death in the heart. Degradation of damaged mitochondria by mitophagy is essential for the maintenance of healthy mitochondria and survival. Here, we show that mitophagy during myocardial ischemia was mediated predominantly through aut...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Saito, Toshiro, Nah, Jihoon, Oka, Shin-ichi, Mukai, Risa, Monden, Yoshiya, Maejima, Yasuhiro, Ikeda, Yoshiyuki, Sciarretta, Sebastiano, Liu, Tong, Li, Hong, Baljinnyam, Erdene, Fraidenraich, Diego, Fritzky, Luke, Zhai, Peiyong, Ichinose, Shizuko, Isobe, Mitsuaki, Hsu, Chiao-Po, Kundu, Mondira, Sadoshima, Junichi
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355232/
https://ncbi.nlm.nih.gov/pubmed/30511961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122035
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