Llwytho...

Regulation of Autophagy by Beclin 1 in the Heart

Dysregulation of autophagy in cardiomyocytes is implicated in various heart disease conditions. Beclin 1, a mammalian ortholog of yeast Atg6 and a core component of the autophagy machinery, plays a central role in the regulation of autophagy through activation of Vps34. Beclin 1’s ability to activat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Cell Cardiol
Prif Awduron: Maejima, Yasuhiro, Isobe, Mitsuaki, Sadoshima, Junichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861696/
https://ncbi.nlm.nih.gov/pubmed/26546165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.10.032
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