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Regulation of Autophagy by Beclin 1 in the Heart
Dysregulation of autophagy in cardiomyocytes is implicated in various heart disease conditions. Beclin 1, a mammalian ortholog of yeast Atg6 and a core component of the autophagy machinery, plays a central role in the regulation of autophagy through activation of Vps34. Beclin 1’s ability to activat...
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| Publicat a: | J Mol Cell Cardiol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861696/ https://ncbi.nlm.nih.gov/pubmed/26546165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.10.032 |
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