Structural basis of Ca(2+)-dependent activation and lipid transport by a TMEM16 scramblase

The lipid distribution of plasma membranes of eukaryotic cells is asymmetric and phospholipid scramblases disrupt this asymmetry by mediating the rapid, nonselective transport of lipids down their concentration gradients. As a result, phosphatidylserine is exposed to the outer leaflet of membrane, a...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Falzone, Maria E, Rheinberger, Jan, Lee, Byoung-Cheol, Peyear, Thasin, Sasset, Linda, Raczkowski, Ashleigh M, Eng, Edward T, Di Lorenzo, Annarita, Andersen, Olaf S, Nimigean, Crina M, Accardi, Alessio
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2019
Предметы:
Structural Biology and Molecular Biophysics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355197/
https://ncbi.nlm.nih.gov/pubmed/30648972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43229
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы