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Diet-induced β-cell insulin resistance results in reversible loss of functional β-cell mass
Although convincing in genetic models, the relevance of β-cell insulin resistance in diet-induced type 2 diabetes (T2DM) remains unclear. Exemplified by diabetes-prone, male, C57B1/6J mice being fed different combinations of Western-style diet, we show that β-cell insulin resistance occurs early dur...
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| 出版年: | FASEB J |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Federation of American Societies for Experimental Biology
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355083/ https://ncbi.nlm.nih.gov/pubmed/29957055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800826R |
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