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Individual response to mTOR inhibition in delaying replicative senescence of mesenchymal stromal cells
BACKGROUND AIMS: Delaying replicative senescence and extending lifespan of human mesenchymal stromal cells (MSCs) may enhance their potential for tissue engineering and cell based therapies. Accumulating evidence suggests that inhibitors of the mTOR signaling pathway, such as rapamycin, constitute p...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6354956/ https://ncbi.nlm.nih.gov/pubmed/30703123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204784 |
| Oznake: |
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