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Reductive α-borylation of α,β-unsaturated esters using NHC–BH(3) activated by I(2) as a metal-free route to α-boryl esters

Useful α-boryl esters can be synthesized in one step from α,β-unsaturated esters using just a simple to access NHC–BH(3) (NHC = N-heterocyclic carbene) and catalytic I(2). The scope of this reductive α-borylation methodology is excellent and includes a range of alkyl, aryl substituted and cyclic and...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Radcliffe, James E., Fasano, Valerio, Adams, Ralph W., You, Peiran, Ingleson, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354834/
https://ncbi.nlm.nih.gov/pubmed/30809360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04305a
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