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Transduction of Adeno-Associated Virus Vectors Targeting Hair Cells and Supporting Cells in the Neonatal Mouse Cochlea

Adeno-associated virus (AAV) is the preferred vector for gene therapy of hereditary deafness, and different viral serotypes, promoters and transduction pathways can influence the targeting of AAV to different types of cells and the expression levels of numerous exogenous genes. To determine the tran...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Gu, Xi, Chai, Renjie, Guo, Luo, Dong, Biao, Li, Wenyan, Shu, Yilai, Huang, Xinsheng, Li, Huawei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353798/
https://ncbi.nlm.nih.gov/pubmed/30733670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00008
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