Transduction of Adeno-Associated Virus Vectors Targeting Hair Cells and Supporting Cells in the Neonatal Mouse Cochlea

Adeno-associated virus (AAV) is the preferred vector for gene therapy of hereditary deafness, and different viral serotypes, promoters and transduction pathways can influence the targeting of AAV to different types of cells and the expression levels of numerous exogenous genes. To determine the tran...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Gu, Xi, Chai, Renjie, Guo, Luo, Dong, Biao, Li, Wenyan, Shu, Yilai, Huang, Xinsheng, Li, Huawei
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353798/
https://ncbi.nlm.nih.gov/pubmed/30733670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00008
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