Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo

Loss of cochlear hair cells in mammals is currently believed to be permanent, resulting in hearing impairment that affects more than 10% of the population. Here, we developed two genetic strategies to ablate neonatal mouse cochlear hair cells in vivo. Both Pou4f3(DTR/+) and Atoh1-CreER™; ROSA26(DTA/...

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Detalhes bibliográficos
Main Authors: Cox, Brandon C., Chai, Renjie, Lenoir, Anne, Liu, Zhiyong, Zhang, LingLi, Nguyen, Duc-Huy, Chalasani, Kavita, Steigelman, Katherine A., Fang, Jie, Cheng, Alan G., Zuo, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2014
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912828/
https://ncbi.nlm.nih.gov/pubmed/24496619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.103036
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