Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo

Loss of cochlear hair cells in mammals is currently believed to be permanent, resulting in hearing impairment that affects more than 10% of the population. Here, we developed two genetic strategies to ablate neonatal mouse cochlear hair cells in vivo. Both Pou4f3(DTR/+) and Atoh1-CreER™; ROSA26(DTA/...

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Dettagli Bibliografici
Autori principali: Cox, Brandon C., Chai, Renjie, Lenoir, Anne, Liu, Zhiyong, Zhang, LingLi, Nguyen, Duc-Huy, Chalasani, Kavita, Steigelman, Katherine A., Fang, Jie, Cheng, Alan G., Zuo, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2014
Soggetti:
Stem Cells and Regeneration
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912828/
https://ncbi.nlm.nih.gov/pubmed/24496619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.103036
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