Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo

Loss of cochlear hair cells in mammals is currently believed to be permanent, resulting in hearing impairment that affects more than 10% of the population. Here, we developed two genetic strategies to ablate neonatal mouse cochlear hair cells in vivo. Both Pou4f3(DTR/+) and Atoh1-CreER™; ROSA26(DTA/...

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Hlavní autoři: Cox, Brandon C., Chai, Renjie, Lenoir, Anne, Liu, Zhiyong, Zhang, LingLi, Nguyen, Duc-Huy, Chalasani, Kavita, Steigelman, Katherine A., Fang, Jie, Cheng, Alan G., Zuo, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2014
Témata:
Stem Cells and Regeneration
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912828/
https://ncbi.nlm.nih.gov/pubmed/24496619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.103036
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