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Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway
The activation of cochlear progenitor cells is a promising approach for hair cell (HC) regeneration and hearing recovery. The mechanisms underlying the initiation of proliferation of postnatal cochlear progenitor cells and their transdifferentiation to HCs remain to be determined. We show that Notch...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291673/ https://ncbi.nlm.nih.gov/pubmed/25535395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415901112 |
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