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Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway
The activation of cochlear progenitor cells is a promising approach for hair cell (HC) regeneration and hearing recovery. The mechanisms underlying the initiation of proliferation of postnatal cochlear progenitor cells and their transdifferentiation to HCs remain to be determined. We show that Notch...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291673/ https://ncbi.nlm.nih.gov/pubmed/25535395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415901112 |
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