Hedgehog Signaling Promotes the Proliferation and Subsequent Hair Cell Formation of Progenitor Cells in the Neonatal Mouse Cochlea

Hair cell (HC) loss is the major cause of permanent sensorineural hearing loss in mammals. Unlike lower vertebrates, mammalian cochlear HCs cannot regenerate spontaneously after damage, although the vestibular system does maintain limited HC regeneration capacity. Thus HC regeneration from the damag...

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Publicado en:Front Mol Neurosci
Autores principales: Chen, Yan, Lu, Xiaoling, Guo, Luo, Ni, Wenli, Zhang, Yanping, Zhao, Liping, Wu, Lingjie, Sun, Shan, Zhang, Shasha, Tang, Mingliang, Li, Wenyan, Chai, Renjie, Li, Huawei
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742997/
https://ncbi.nlm.nih.gov/pubmed/29311816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00426
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