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Hedgehog Signaling Promotes the Proliferation and Subsequent Hair Cell Formation of Progenitor Cells in the Neonatal Mouse Cochlea

Hair cell (HC) loss is the major cause of permanent sensorineural hearing loss in mammals. Unlike lower vertebrates, mammalian cochlear HCs cannot regenerate spontaneously after damage, although the vestibular system does maintain limited HC regeneration capacity. Thus HC regeneration from the damag...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Chen, Yan, Lu, Xiaoling, Guo, Luo, Ni, Wenli, Zhang, Yanping, Zhao, Liping, Wu, Lingjie, Sun, Shan, Zhang, Shasha, Tang, Mingliang, Li, Wenyan, Chai, Renjie, Li, Huawei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742997/
https://ncbi.nlm.nih.gov/pubmed/29311816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00426
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