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Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activation

Idiopathic pulmonary fibrosis (IPF) is an aging‐associated disease with poor prognosis. Currently, there are no effective drugs for preventing the disease process. The mechanisms underlying the role of alveolar epithelial cell (AEC) senescence in the pathogenesis of IPF remain poorly understood. We...

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Podrobná bibliografie
Vydáno v:Aging Cell
Hlavní autoři: Tian, Yaqiong, Li, Hui, Qiu, Ting, Dai, Jinghong, Zhang, Yingwei, Chen, Jingyu, Cai, Hourong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351835/
https://ncbi.nlm.nih.gov/pubmed/30548445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12858
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