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Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activation

Idiopathic pulmonary fibrosis (IPF) is an aging‐associated disease with poor prognosis. Currently, there are no effective drugs for preventing the disease process. The mechanisms underlying the role of alveolar epithelial cell (AEC) senescence in the pathogenesis of IPF remain poorly understood. We...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Tian, Yaqiong, Li, Hui, Qiu, Ting, Dai, Jinghong, Zhang, Yingwei, Chen, Jingyu, Cai, Hourong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351835/
https://ncbi.nlm.nih.gov/pubmed/30548445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12858
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