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Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activation

Idiopathic pulmonary fibrosis (IPF) is an aging‐associated disease with poor prognosis. Currently, there are no effective drugs for preventing the disease process. The mechanisms underlying the role of alveolar epithelial cell (AEC) senescence in the pathogenesis of IPF remain poorly understood. We...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Tian, Yaqiong, Li, Hui, Qiu, Ting, Dai, Jinghong, Zhang, Yingwei, Chen, Jingyu, Cai, Hourong
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351835/
https://ncbi.nlm.nih.gov/pubmed/30548445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12858
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