PTEN loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation

Idiopathic pulmonary fibrosis (IPF) is an aging-associated disease with poor prognosis. The mechanisms underlying the role of alveolar epithelial cell (AEC) senescence in IPF remain poorly understood. We aimed to investigate if PTEN/Akt activates AEC senescence to induce pulmonary fibrosis. We inves...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Qiu, Ting, Tian, Yaqiong, Gao, Yujuan, Ma, Miao, Li, Hui, Liu, Xiaoqin, Wu, Hongyan, Zhang, Yingwei, Ding, Hui, Cao, Mengshu, Zhang, Ji, Dai, Jinghong, Chen, Jingyu, Cai, Hourong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781970/
https://ncbi.nlm.nih.gov/pubmed/31527305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102262
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