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REGULATION OF PTEN EXPRESSION IN INTESTINAL EPITHELIAL CELLS BY JNK ACTIVATION AND NF-κB INHIBITION
The tumor suppressor protein PTEN plays an important role in intestinal cell proliferation and differentiation and tumor suppression by antagonizing phosphatidylinositol 3-kinase (PI3K). Despite its importance, the molecular mechanisms regulating PTEN expression are largely undefined. Here, we show...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2649758/ https://ncbi.nlm.nih.gov/pubmed/17699782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-0187 |
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