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REGULATION OF PTEN EXPRESSION IN INTESTINAL EPITHELIAL CELLS BY JNK ACTIVATION AND NF-κB INHIBITION

The tumor suppressor protein PTEN plays an important role in intestinal cell proliferation and differentiation and tumor suppression by antagonizing phosphatidylinositol 3-kinase (PI3K). Despite its importance, the molecular mechanisms regulating PTEN expression are largely undefined. Here, we show...

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Autori principali: Wang, QingDing, Zhou, Yuning, Wang, Xiaofu, Chung, Dai H., Evers, B. Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649758/
https://ncbi.nlm.nih.gov/pubmed/17699782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-0187
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