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Female XX sex chromosomes increase survival and extend lifespan in aging mice

Female longevity is observed in humans and much of the animal kingdom, but its causes remain elusive. Using a genetic manipulation that generates XX and XY mice, each with either ovaries or testes, we show that the female XX sex chromosome complement increases survival during aging in male and femal...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Davis, Emily J., Lobach, Iryna, Dubal, Dena B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351820/
https://ncbi.nlm.nih.gov/pubmed/30560587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12871
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