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Female XX sex chromosomes increase survival and extend lifespan in aging mice
Female longevity is observed in humans and much of the animal kingdom, but its causes remain elusive. Using a genetic manipulation that generates XX and XY mice, each with either ovaries or testes, we show that the female XX sex chromosome complement increases survival during aging in male and femal...
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| Udgivet i: | Aging Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351820/ https://ncbi.nlm.nih.gov/pubmed/30560587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12871 |
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