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Female XX sex chromosomes increase survival and extend lifespan in aging mice

Female longevity is observed in humans and much of the animal kingdom, but its causes remain elusive. Using a genetic manipulation that generates XX and XY mice, each with either ovaries or testes, we show that the female XX sex chromosome complement increases survival during aging in male and femal...

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Dades bibliogràfiques
Publicat a:Aging Cell
Autors principals: Davis, Emily J., Lobach, Iryna, Dubal, Dena B.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351820/
https://ncbi.nlm.nih.gov/pubmed/30560587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12871
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