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Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis
Multiple sclerosis is a chronic autoimmune demyelinating disorder of the CNS. Immune-mediated oligodendrocyte cell loss contributes to multiple sclerosis pathogenesis, such that oligodendrocyte-protective strategies represent a promising therapeutic approach. The integrated stress response, which is...
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| Veröffentlicht in: | Brain |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351782/ https://ncbi.nlm.nih.gov/pubmed/30657878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy322 |
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