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Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment
The inflammatory environment of demyelinated lesions in multiple sclerosis (MS) patients contributes to remyelination failure. Inflammation activates a cytoprotective pathway, the integrated stress response (ISR), but it remains unclear whether enhancing the ISR can improve remyelination in an infla...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7987340/ https://ncbi.nlm.nih.gov/pubmed/33752802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65469 |
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