Pre-clinical and Clinical Implications of “Inside-Out” vs. “Outside-In” Paradigms in Multiple Sclerosis Etiopathogenesis

Multiple Sclerosis (MS) is an immune-mediated neurological disorder, characterized by central nervous system (CNS) inflammation, oligodendrocyte loss, demyelination, and axonal degeneration. Although autoimmunity, inflammatory demyelination and neurodegeneration underlie MS, the initiating event has...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Titus, Haley E., Chen, Yanan, Podojil, Joseph R., Robinson, Andrew P., Balabanov, Roumen, Popko, Brian, Miller, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654287/
https://ncbi.nlm.nih.gov/pubmed/33192332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.599717
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