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Tsc1 ablation in Prx1 and Osterix lineages causes renal cystogenesis in mouse
Tuberous Sclerosis Complex (TSC) is caused by mutations in TSC1 or TSC2, which encode negative regulators of the mTOR signaling pathway. The renal abnormalities associated with TSC include angiomyolipoma, cysts, and renal cell carcinoma. Here we report that specific ablation of Tsc1 using the mesenc...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351533/ https://ncbi.nlm.nih.gov/pubmed/30696882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37139-9 |
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