Tuberin-deficiency downregulates N-cadherin and upregulates vimentin in kidney tumor of TSC patients

Angiomyolipomas (AMLs) are associated with cell fibrosis in kidney of Tuberous Sclerosis Complex patients. The mechanism by which the fibrotic proteins accumulated in AMLs has not been explored. In the present study, we investigated the role of Akt/tuberin/mTOR pathway in the regulation cell fibrosi...

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Main Authors: Liang, Sitai, Salas, Tiffanie, Gencaslan, Emre, Li, Baojie, Habib, Samy L.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196174/
https://ncbi.nlm.nih.gov/pubmed/25149531
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