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Tuberin-deficiency downregulates N-cadherin and upregulates vimentin in kidney tumor of TSC patients

Angiomyolipomas (AMLs) are associated with cell fibrosis in kidney of Tuberous Sclerosis Complex patients. The mechanism by which the fibrotic proteins accumulated in AMLs has not been explored. In the present study, we investigated the role of Akt/tuberin/mTOR pathway in the regulation cell fibrosi...

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Autors principals: Liang, Sitai, Salas, Tiffanie, Gencaslan, Emre, Li, Baojie, Habib, Samy L.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196174/
https://ncbi.nlm.nih.gov/pubmed/25149531
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