Macrophage-specific HIF-1α contributes to impaired autophagic flux in non-alcoholic steatohepatitis

Inflammatory cell activation drives diverse cellular programming during hepatic diseases. Hypoxia-inducible factors (HIFs) have recently been identified as important regulators of immunity and inflammation. In non-alcoholic steatohepatitis (NASH), HIF-1α is upregulated in hepatocytes where it induce...

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Publicado no:Hepatology
Main Authors: Wang, Xiaojing, Ribeiro, Marcelle, Iracheta-Vellve, Arvin, Lowe, Patrick, Ambade, Aditya, Satishchandran, Abhishek, Bukong, Terence, Catalano, Donna, Kodys, Karen, Szabo, Gyongyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351177/
https://ncbi.nlm.nih.gov/pubmed/30102772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30215
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