Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease

The spectrum of alcoholic liver disease (ALD) is a major cause of mortality with limited therapies available. Because alcohol targets numerous signaling pathways in hepatocytes and in immune cells, the identification of a master regulatory target that modulates multiple signaling processes is attrac...

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Vydáno v:Hepatology
Hlavní autoři: Bukong, Terence N., Iracheta-Vellve, Arvin, Saha, Banishree, Ambade, Aditya, Satishchandran, Abhishek, Gyongyosi, Benedek, Lowe, Patrick, Catalano, Donna, Kodys, Karen, Szabo, Gyongyi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033691/
https://ncbi.nlm.nih.gov/pubmed/27302565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28680
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