Therapeutic benefits of SYK inhibitor administration on binge drinking-induced alcoholic liver injury, steatosis and inflammation in mice

BACKGROUND: Binge drinking is increasingly recognized as an important cause of liver disease with limited therapeutic options for patients. Binge alcohol use, similar to chronic alcohol consumption, induces numerous deregulated signaling events that drive liver damage, steatosis and inflammation. In...

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Bibliographic Details
Published in:Alcohol Clin Exp Res
Main Authors: Bukong, Terence N., Iracheta-Vellve, Arvin, Gyongyosi, Benedek, Ambade, Aditya, Catalano, Donna, Kodys, Karen, Szabo, Gyongyi
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930418/
https://ncbi.nlm.nih.gov/pubmed/27177528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13096
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