Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice

BACKGROUND: Alcohol-induced intestinal dysbiosis disrupts homeostatic gut-liver axis function and is essential in the development of alcoholic liver disease. Here, we investigate changes in enteric microbiome composition in a model of early alcoholic steatohepatitis and dissect the pathogenic role o...

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Veröffentlicht in:PLoS One
Hauptverfasser: Lowe, Patrick P., Gyongyosi, Benedek, Satishchandran, Abhishek, Iracheta-Vellve, Arvin, Ambade, Aditya, Kodys, Karen, Catalano, Donna, Ward, Doyle V., Szabo, Gyongyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370121/
https://ncbi.nlm.nih.gov/pubmed/28350851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174544
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