Hepatocellular carcinoma is accelerated by NASH involving M2 macrophage polarization mediated by hif-1αinduced IL-10

Obesity-related inflammation promotes cancer development. Tissue resident macrophages affect tumor progression and the tumor micro-environment favors polarization into alternatively activated macrophages (M2) that facilitate tumor invasiveness. Here, we dissected the role of western diet-induced NAS...

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Vydáno v:Oncoimmunology
Hlavní autoři: Ambade, Aditya, Satishchandran, Abhishek, Saha, Banishree, Gyongyosi, Benedek, Lowe, Patrick, Kodys, Karen, Catalano, Donna, Szabo, Gyongyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087291/
https://ncbi.nlm.nih.gov/pubmed/27853646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1221557
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