Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

Integrative analysis of multi-omics layers at single cell level is critical for accurate dissection of cell-to-cell variation within certain cell populations. Here we report scCAT-seq, a technique for simultaneously assaying chromatin accessibility and the transcriptome within the same single cell....

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Publicado no:Nat Commun
Main Authors: Liu, Longqi, Liu, Chuanyu, Quintero, Andrés, Wu, Liang, Yuan, Yue, Wang, Mingyue, Cheng, Mengnan, Leng, Lizhi, Xu, Liqin, Dong, Guoyi, Li, Rui, Liu, Yang, Wei, Xiaoyu, Xu, Jiangshan, Chen, Xiaowei, Lu, Haorong, Chen, Dongsheng, Wang, Quanlei, Zhou, Qing, Lin, Xinxin, Li, Guibo, Liu, Shiping, Wang, Qi, Wang, Hongru, Fink, J. Lynn, Gao, Zhengliang, Liu, Xin, Hou, Yong, Zhu, Shida, Yang, Huanming, Ye, Yunming, Lin, Ge, Chen, Fang, Herrmann, Carl, Eils, Roland, Shang, Zhouchun, Xu, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349937/
https://ncbi.nlm.nih.gov/pubmed/30692544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08205-7
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