Tumor Copy Number Deconvolution Integrating Bulk and Single-Cell Sequencing Data

Characterizing intratumor heterogeneity (ITH) is crucial to understanding cancer development, but it is hampered by limits of available data sources. Bulk DNA sequencing is the most common technology to assess ITH, but involves the analysis of a mixture of many genetically distinct cells in each sam...

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Detalhes bibliográficos
Publicado no:J Comput Biol
Main Authors: Lei, Haoyun, Lyu, Bochuan, Gertz, E. Michael, Schäffer, Alejandro A., Shi, Xulian, Wu, Kui, Li, Guibo, Xu, Liqin, Hou, Yong, Dean, Michael, Schwartz, Russell
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185355/
https://ncbi.nlm.nih.gov/pubmed/32181683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2019.0302
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