An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos

Human pre-implantation embryonic development involves extensive changes in chromatin structure and transcriptional activity. Here, we report on LiCAT-seq, a technique that enables simultaneous profiling of chromatin accessibility and gene expression with ultra-low input of cells, and map the chromat...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Liu, Longqi, Leng, Lizhi, Liu, Chuanyu, Lu, Changfu, Yuan, Yue, Wu, Liang, Gong, Fei, Zhang, Shuoping, Wei, Xiaoyu, Wang, Mingyue, Zhao, Lei, Hu, Liang, Wang, Jian, Yang, Huanming, Zhu, Shida, Chen, Fang, Lu, Guangxiu, Shang, Zhouchun, Lin, Ge
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341076/
https://ncbi.nlm.nih.gov/pubmed/30664750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08244-0
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