Pancreatic fibroblast growth factor 21 protects against type 2 diabetes in mice by promoting insulin expression and secretion in a PI3K/Akt signaling‐dependent manner

Fibroblast growth factor 21 (FGF21) is important in glucose, lipid homeostasis and insulin sensitivity. However, it remains unknown whether FGF21 is involved in insulin expression and secretion that are dysregulated in type 2 diabetes mellitus (T2DM). In this study, we found that FGF21 was down‐regu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Mol Med
Egile Nagusiak: Pan, Yingying, Wang, Baile, Zheng, Jujia, Xiong, Rongrong, Fan, Zhichao, Ye, Yanna, Zhang, Saisai, Li, Qinyao, Gong, Fanghua, Wu, Chaoming, Lin, Zhuofeng, Li, Xiaokun, Pan, Xuebo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349243/
https://ncbi.nlm.nih.gov/pubmed/30461198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14007
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