SIRT1 Mediates Effects of FGF21 to Ameliorate Cisplatin-Induced Acute Kidney Injury

Acute kidney injury (AKI) is a common complication in cancer patients. Kidney function is closely related to patients’ quality of life and tumor prognosis. Cisplatin is a highly effective anti-tumor drug. However, the use of cisplatin is limited by its nephrotoxicity. It has been reported that FGF21...

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Vydáno v:Front Pharmacol
Hlavní autoři: Chen, Qiongzhen, Ma, Junfeng, Yang, Xiaoning, Li, Qinyao, Lin, Zhuofeng, Gong, Fanghua
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076185/
https://ncbi.nlm.nih.gov/pubmed/32210821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00241
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